|"Effect of Non-Leisure Physical Activity on Mortality in U.S. Adults: Does Propensity Score Matching Make a Difference?"
Jeehyun Park and Louise B. Russell
Annals of Epidemiology
To reanalyze results reported in 2008, using propensity score matching, to test the treatment effect of non-leisure physical activity on survival.|
McCullagh's ordinal logit model was used to estimate propensity scores, separately for adults aged 35–59 and 60–74 years at baseline in the National Health and Nutrition Examination Survey I Epidemiologic Followup Study, for three levels of non-leisure activity. Each untreated adult (low non-leisure activity) was matched to two treated adults from the same age group, one with moderate and one with high non-leisure activity. Multivariable Cox proportional hazard regressions were fitted to the matched samples and compared with regressions fitted to unmatched samples.
Except for moderate leisure-time activity and age, observed covariates were well balanced after matching. For adults aged 35–59 years, matched regressions showed smaller mortality reductions: 23% for moderate and 32% for high non-leisure activity, compared with low non-leisure activity. For adults aged 60–74 years, matched regressions showed a smaller mortality reduction for moderate non-leisure activity (29%) but a larger reduction for high non-leisure activity (47%).
In line with published reviews of conventional multivariable analysis versus propensity score matching, Cox regressions on matched and unmatched samples produced similar estimates of treatment effects for non-leisure activity, but the estimates from matched regressions were usually smaller.Jeehyun Park and Louise B. Russell. (2012). "Effect of Non-Leisure Physical Activity on Mortality in U.S. Adults: Does Propensity Score Matching Make a Difference?" Annals of Epidemiology, 22 (8): 575-580.